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Home / Primary Antibodies / Polyclonal Antibodies

IRF9 antibody

SKU : BHA10804389

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Mfr.No.	FNab04397
Alternative Names	ISGF3G
Background	Transcription factor that mediates signaling by type I IFNs(IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases(TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element(ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Host	Rabbit
Immunogen	interferon regulatory factor 9
Isotype	IgG
Molecular Weight	48kd
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	interferon regulatory factor 9, IRF 9, IRF9, ISGF 3 gamma, ISGF3, ISGF3 p48 subunit, ISGF3G, p48

Uniprot	Q00978
Gene Id	10379
Research Area	Epigenetics, Signal Transduction, Metabolism, Cancer, Immunology

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF, IP
Description	ELISA ; WB ; IHC ; IF ; IP
Tested Application	WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804389	FNab04397	100ug	$260		Add to Cart

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