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Home / Primary Antibodies / Polyclonal Antibodies

IRF4 antibody

SKU : BHA10804382

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Mfr.No.	FNab04390
Alternative Names	MUM1
Background	Transcriptional activator. Binds to the interferon-stimulated response element(ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence(5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes(By similarity).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcriptional activator. Binds to the interferon- stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).
Host	Rabbit
Immunogen	interferon regulatory factor 4
Isotype	IgG
Molecular Weight	52 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	MUM1

Uniprot	Q15306
Gene Id	3662
Research Area	Epigenetics, Cancer, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB, IP
Description	ELISA ; IHC ; WB ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804382	FNab04390	100ug	$260		Add to Cart

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