This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
Clonality
polyclonal
Host
Rabbit
Immunogen
IRAK3
Immunogen Region
transducin-like enhancer of split 1
Isotype
IgG
Molecular Weight
68kDa
Reactivity
Human
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Synonyms
ASRT5, IRAKM
Uniprot
Q9Y616
Gene Id
11213
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10855.pdf" target="_blank">Data Sheet</ a>