Involucrin is a protein precursor of the epidermal cornified envelope that is assembled in the outermost layers of the epidermis. Involucrin expression is restricted to the suprabasal epidermal layers (spinous and granular layers) during normal keratinocyte differentiation and is a useful marker of terminal differentiation. The predicted MW of involucrin is 68 kDa, while different reports provided variable results ranging from 90-140 kDa.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
involucrin
Isotype
IgG
Molecular Weight
80 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
involucrin, IVL
Uniprot
P07476
Research Area
Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)