Component of the Integrator complex, a complex involved in the small nuclear RNAs(snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain(CTD) of RNA polymerase II largest subunit(POLR2A) and is recruited to the U1 and U2 snRNAs genes. Plays a role in DNA damage response(DDR) signaling during the S phase.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Plays a role in DNA damage response (DDR) signaling during the S phase.
Host
Rabbit
Immunogen
integrator complex subunit 7
Isotype
IgG
Molecular Weight
107kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
C1orf73
Uniprot
Q9NVH2
Gene Id
25896
Research Area
epigenetics
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)