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Home / Primary Antibodies / Polyclonal Antibodies

Integrin alpha-4 antibody

SKU : BHA10804338

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Mfr.No.	FNab04346
Alternative Names	CD49D ; IA4 ; Integrinalpha4 ; IntegrinalphaIV ; ITGA4 ; VLA4subunitalpha
Background	ITGA4, also named as CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1 and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. I It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
Categories	Primary Antibodies
Clonality	polyclonal
Description	ITGA4, also named as CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1 and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. I It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
Host	Rabbit
Immunogen	integrin, alpha 4
Isotype	IgG
Molecular Weight	140 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CD49D, IA4, Integrin alpha 4, Integrin alpha IV, ITGA4, VLA 4 subunit alpha

Uniprot	P13612
Gene Id	3676
Research Area	Stem Cells, Immunology, Cardiovascular
Weight	115kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:1000-1:10000
IHC	1:20-1:200

Tested Application

WB: 1500-1:2000; IHC: 1:20-1:200

Manual	FNab04346.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804338	FNab04346	100ug	$240		Add to Cart

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