Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
Host
Rabbit
Immunogen
insulin receptor-related receptor
Isotype
IgG
Molecular Weight
150-155kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
IRR
Uniprot
P14616
Gene Id
3645
Research Area
Developmental biology, Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)