The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Clonality
polyclonal
Host
Rabbit
Immunogen
IL2RA
Immunogen Region
IL2RA
Isotype
IgG
Molecular Weight
30 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000
Synonyms
CD25, IDDM10, IL2R, IMD41, p55, TCGFR
Uniprot
P01589
Gene Id
3550
Research Area
Immunology, Cancer, Stem Cells
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09878.pdf" target="_blank">Data Sheet</ a>