Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.
Host
Rabbit
Immunogen
interleukin 11 receptor, alpha
Isotype
IgG
Molecular Weight
45 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
IL 11 receptor subunit alpha, IL 11R alpha, IL 11R subunit alpha, IL 11RA, IL11RA, interleukin 11 receptor, alpha
Uniprot
Q14626
Gene Id
3590
Research Area
Developmental biology, Immunology, Cardiovascular, Signal Transduction
Weight
45kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)