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Home / Primary Antibodies / Polyclonal Antibodies

IL11 antibody

SKU : BHA10804209

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Mfr.No.	FNab04216
Background	Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production(PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation(PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
Host	Rabbit
Immunogen	interleukin 11
Isotype	IgG
Molecular Weight	25 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	Adipogenesis inhibitory factor, AGIF, IL 11, IL11, interleukin 11, Oprelvekin

Uniprot	P20809
Gene Id	3589
Research Area	Immunology, Cardiovascular

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:200-1:1000

Manual	FNab04216.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804209	FNab04216	100ug	$280		Add to Cart

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