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Home / Primary Antibodies / Polyclonal Antibodies

IL10RA antibody

SKU : BHA10804206

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Mfr.No.	FNab04213
Alternative Names	IL10R
Background	The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Receptor for IL10; binds IL10 with a high affinity.
Host	Rabbit
Immunogen	interleukin 10 receptor, alpha
Isotype	IgG
Molecular Weight	72 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	IL10R

Uniprot	Q13651
Gene Id	3587
Research Area	Immunology, Cardiovascular, Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, FC
Description	ELISA ; WB ; FC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab04213.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804206	FNab04213	100ug	$280		Add to Cart

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