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Home / Primary Antibodies / Monoclonal Antibodies

IL1 Beta antibody

SKU : BHA10809752

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Mfr.No.	FNab04210
Background	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Clonality	monoclonal
Host	Mouse
Immunogen	interleukin 1, beta
Immunogen Region	interleukin 1, beta
Isotype	IgG1
Molecular Weight	35kDa
Reactivity	Human
Recommended Dilution	WB: 1:1000-1:4000; IHC: 1:50-1:500
Synonyms	IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL1B, IL1beta, IL1F2, IL-1beta, Interleukin 1 beta, interleukin 1, beta

Uniprot	P01584
Gene Id	3553
Clone No	9G5
Research Area	Immunology, Cardiovascular, Signal Transduction, Neuroscience

Form	liquid
Purification	Protein G purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:1000-1:4000; IHC: 1:50-1:500

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809752	FNab04210	100ug	$300		Add to Cart

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