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Home / Primary Antibodies / Polyclonal Antibodies

IL-6 antibody

SKU : BHA10804274

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Mfr.No.	FNab04282
Alternative Names	Bcellstimulatoryfactor2 ; BSF2 ; BSF2 ; CDF ; CTLdifferentiationfactor ; HGF ; HSF ; Hybridomagrowthfactor ; IFNbeta2 ; IFNB2 ; IL6
Background	Interleukin-6(IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
Host	Rabbit
Immunogen	interleukin 6(interferon, beta 2)
Isotype	IgG
Molecular Weight	24 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HGF, HSF, Hybridoma growth factor, IFN beta 2, IFNB2, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6

Uniprot	P05231
Gene Id	3569
Research Area	Immunology, Cardiovascular, Signal Transduction, Neuroscience
Weight	25kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:50-1:200

Tested Application

WB: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:200

Manual	FNab04282.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804274	FNab04282	100ug	$280		Add to Cart

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