Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2- dependent manner.
Host
Rabbit
Immunogen
IKAROS family zinc finger 3(Aiolos)
Isotype
IgG
Molecular Weight
58-70kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ZNFN1A3
Uniprot
Q9UKT9
Gene Id
22806
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)