The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
Clonality
polyclonal
Host
Rabbit
Immunogen
insulin-like growth factor I
Immunogen Region
insulin-like growth factor I
Isotype
IgG
Molecular Weight
21 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Synonyms
IGF-I, IGFI, MGF
Uniprot
P05019
Gene Id
3479
Research Area
Epigenetics, Developmental biology, Signal Transduction, Metabolism, Cardiovascular, Stem Cells, Neuroscience
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09936.pdf" target="_blank">Data Sheet</ a>