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Home / Primary Antibodies / Polyclonal Antibodies

IFT57 antibody

SKU : BHA10804154

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Mfr.No.	FNab04160
Alternative Names	DERP8 ; ESRRBL1 ; HIPPI
Background	Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway(By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8(CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Host	Rabbit
Immunogen	intraflagellar transport 57 homolog(Chlamydomonas)
Isotype	IgG
Molecular Weight	49kd
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	DERP8, ESRRBL1, HIPPI

Uniprot	Q9NWB7
Gene Id	55081
Research Area	Metabolism, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804154	FNab04160	100ug	$240		Add to Cart

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