Small GTPase-like component of the intraflagellar transport(IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6(PubMed:25443296). Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6(PubMed:25443296). Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6 (PubMed:25443296). Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6 (PubMed:25443296). Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25 (By similarity).
Host
Rabbit
Immunogen
RAB, member of RAS oncogene family-like 4
Isotype
IgG
Molecular Weight
20 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
RABL4, RAYL
Uniprot
Q9BW83
Gene Id
11020
Research Area
Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)