This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
Clonality
polyclonal
Host
Rabbit
Immunogen
Interferon beta
Immunogen Region
Interferon beta
Isotype
IgG
Molecular Weight
22 kDa
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000
Synonyms
IFNB1, IFB, IFF, IFN-beta, IFNB
Uniprot
P01574
Gene Id
3456
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10475.pdf" target="_blank">Data Sheet</ a>