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Home / Primary Antibodies / Polyclonal Antibodies

IFIT5 antibody

SKU : BHA10804133

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Mfr.No.	FNab04139
Alternative Names	ISG58 ; RI58
Background	Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group(PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP- RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.
Host	Rabbit
Immunogen	interferon-induced protein with tetratricopeptide repeats 5
Isotype	IgG
Molecular Weight	56-58 kDa, 48 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	ISG58, RI58

Antigen	IFIT5
Uniprot	Q13325
Gene Id	24138
Research Area	Immunology

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804133	FNab04139	100ug	$280		Add to Cart

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