Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.This antibody is a rabbit polyclonal antibody raised against a full-length human ICT1 protein
Clonality
polyclonal
Host
Rabbit
Immunogen
immature colon carcinoma transcript 1
Immunogen Region
immature colon carcinoma transcript 1
Isotype
IgG
Molecular Weight
21-24 kDa
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Synonyms
Digestion substraction 1, DS 1, DS1, ICT1
Uniprot
Q14197
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10717.pdf" target="_blank">Data Sheet</ a>