ICAM proteins are ligands for the leukocyte adhesion protein LFA-1(integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity).
Host
Rabbit
Immunogen
intercellular adhesion molecule 1
Isotype
IgG
Molecular Weight
85-95 kDa
Reactivity
Mouse, Rat
Regulatory
RUO
Synonyms
CD54, ICAM 1, Icam1, Ly 47, MALA 2
Uniprot
P13597
Gene Id
15894
Research Area
Stem Cells, Immunology, Cardiovascular
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)