ICAM-1(CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues(PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-alpha, INF-gamma, IL-1 and thrombin(PMID: 3086451; 9694714; 15979056).
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
intercellular adhesion molecule 1
Isotype
IgG
Molecular Weight
90 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
Intercellular adhesion molecule 1,Major group rhinovirus receptor,CD54,ICAM1
Uniprot
P05362
Gene Id
3383
Research Area
Stem Cells, Immunology, Cardiovascular
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)