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Home / Primary Antibodies / Polyclonal Antibodies

IBA1 antibody

SKU : BHA10804090

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Mfr.No.	FNab04096
Background	AIF1, also named as G1, IBA1 or daintain/AIF-1, is a 143 amino acid cytoplasmic, inflammation response scaffold protein. It is constitutively expressed in monocytes and macrophages and is known to be involved in macrophage activation. It is a marker of activated macrophage. Despite a lack of detailed knowledge on the in vivo physiological functions of AIF-1, there is growing evidence that shows its aberrant expression contributes to the pathogenesis of many autoimmune diseases, including rheumatoid arthritis. (20944424). AIF1 is an actin-binding protein that enhances membrane ruffling and RAC activation. It enhances lymphocyte migration and the actin-bundling activity of LCP1. AIF1 plays a role in RAC signaling and in phagocytosis and a role in vascular inflammation. AIF1 promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. It is also as a microglial cell marker.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	allograft inflammatory factor 1
Isotype	IgG
Molecular Weight	17 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	AIF 1, AIF1, G1, IBA1, IRT 1, Protein G1

Uniprot	P55008
Gene Id	199
Research Area	Cell Division and Proliferation, Cancer, Neuroscience
Weight	17kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IF, IP, IHC

Description

ELISA ; WB ; IF ; IP ; IHC

Dilution

WB	1:500-1:2000
IP	1:200-1:2000
IHC	1:20-1:200
IF	1:50-1:500

Tested Application

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500

Manual	FNab04096.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804090	FNab04096	100ug	$260		Add to Cart

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