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Home / Primary Antibodies / Polyclonal Antibodies

HSP70 antibody

SKU : BHA10804042

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Mfr.No.	FNab04048
Alternative Names	Heatshock70kDaprotein1A，HSPA1A ; Heatshock70kDaprotein1 ; HSP70-1 ; HSPA1 ; HSX70
Background	HSPA1A, collectively known as HSP70(also referred to HSP72), is a stress-inducible member of heat-shock protein 70(HSP70) proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. Encoded by two closely linked, intronless and stress-inducible genes, HSPA1A and HSPA1B differ by only two amino acids and are believed to be fully interchangeable proteins. HSPA1A is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Generally, HSPA1A is thought to be expressed in unstressed normal cells at low or undetectable levels. Expression of HSPA1A protein can be highly activated by various stressful stimuli. Significant up-regulation of HSPA1A has been found in various tumors. Recently it has been reported that HSPA1A can be constitutively expressed in selected cell types. HSP70 is a useful marker for exosome. This antibody well recognized the endogenous HSP70 protein in multiple cell lines.
Categories	Primary Antibodies
Clonality	polyclonal
Description	HSPA1A , collectively known as HSP70 (also referred to HSP72), is a stress-inducible member of heat-shock protein 70 (HSP70) proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. Encoded by two closely linked, intronless and stress-inducible genes, HSPA1A and HSPA1B differ by only two amino acids and are believed to be fully interchangeable proteins. HSPA1A is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Generally, HSPA1A is thought to be expressed in unstressed normal cells at low or undetectable levels. Expression of HSPA1A protein can be highly activated by various stressful stimuli. Significant up-regulation of HSPA1A has been found in various tumors. Recently it has been reported that HSPA1A can be constitutively expressed in selected cell types. HSP70 is a useful marker for exosome. This antibody well recognized the endogenous HSP70 protein in multiple cell lines. (21373891)
Host	Rabbit
Immunogen	heat shock 70kDa protein 1A
Isotype	IgG
Molecular Weight	66-70 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	Heat shock 70 kDa protein 1A,HSPA1A,Heat shock 70 kDa protein 1,HSP70-1,HSPA1, HSX70

Uniprot	P0DMV8
Research Area	Cancer, Immunology, Metabolism, Neuroscience
Weight	70kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, WB, IF, FC, IP

Description

ELISA ; IHC ; WB ; IF ; FC ; IP

Dilution

WB	1:1000-1:10000
IP	1:500-1:5000
IHC	1:50-1:500
IF	1:20-1:200

Tested Application

WB: 1:1000-1:10000; IP: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:20-1:200

Manual	FNab04048.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804042	FNab04048	100ug	$240		Add to Cart

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