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Home / Primary Antibodies / Polyclonal Antibodies

HPS1 antibody

SKU : BHA10803992

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Mfr.No.	FNab03998
Alternative Names	HPS
Background	This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome-related organelles complex (BLOC)-3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 1. Alternative splicing results in multiple transcript variants. A pseudogene related to this gene is located on chromosome 22.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38 (PubMed:23084991).
Host	Rabbit
Immunogen	Hermansky-Pudlak syndrome 1
Isotype	IgG
Molecular Weight	70-79 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	HPS

Uniprot	Q92902
Gene Id	3257
Research Area	Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100

Manual	FNab03998.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803992	FNab03998	100ug	$280		Add to Cart

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