The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Key enzyme in the degradation of tyrosine.
Host
Rabbit
Immunogen
4-hydroxyphenylpyruvate dioxygenase
Isotype
IgG
Molecular Weight
45 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
PPD
Uniprot
P32754
Gene Id
3242
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)