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Home / Primary Antibodies / Polyclonal Antibodies

HOPX antibody

SKU : BHA10803964

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Mfr.No.	FNab03970
Alternative Names	HOD ; HOP ; LAGY ; NECC1 ; OB1
Background	Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.
Host	Rabbit
Immunogen	HOP homeobox
Isotype	IgG
Molecular Weight	8-12kd
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	HOD, HOP, LAGY, NECC1, OB1

Uniprot	Q9BPY8
Gene Id	84525
Research Area	Developmental biology, Cardiovascular, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IP, WB
Description	ELISA ; IP ; WB
Tested Application	WB: 1:500-1:2000; IF: 1:50-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803964	FNab03970	100ug	$240		Add to Cart

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