Plays a critical role in catalyzing the release of class II-associated invariant chain peptide(CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Host
Rabbit
Immunogen
major histocompatibility complex, class II, DM beta
Isotype
IgG
Molecular Weight
29 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
DMB, RING7
Uniprot
P28068
Gene Id
3109
Research Area
Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)