Plays a critical role in catalyzing the release of class II-associated invariant chain peptide(CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
Host
Rabbit
Immunogen
major histocompatibility complex, class II, DM alpha
Isotype
IgG
Molecular Weight
55-60kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
DMA, RING6
Uniprot
P28067
Research Area
Immunology
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)