Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides(via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
Host
Rabbit
Immunogen
huntingtin interacting protein 1 related
Isotype
IgG
Molecular Weight
120 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
HIP12, KIAA0655
Uniprot
O75146
Gene Id
9026
Research Area
Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)