Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'- CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
Host
Rabbit
Immunogen
hairy/enhancer-of-split related with YRPW motif 2
Isotype
IgG
Molecular Weight
34-36 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
BHLHB32, CHF1, GRL, HERP, HERP1, HRT2
Uniprot
Q9UBP5
Gene Id
23493
Research Area
Developmental biology, Cardiovascular, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)