Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
Host
Rabbit
Immunogen
hexamethylene bis-acetamide inducible 1
Isotype
IgG
Molecular Weight
45 kDa, 70 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CLP1, EDG1, HIS1, MAQ1
Uniprot
O94992
Gene Id
10614
Research Area
Stem Cells, Cardiovascular, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)