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Home / Primary Antibodies / Polyclonal Antibodies

HER2/ErbB2 antibody

SKU : BHA10803828

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Mfr.No.	FNab03834
Background	This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog(avian)
Isotype	IgG
Molecular Weight	185 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	CD340, ERBB2, HER 2, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1

Uniprot	P04626
Gene Id	2064
Research Area	Developmental biology, Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Stem Cells

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Manual	FNab03834.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803828	FNab03834	100ug	$280		Add to Cart

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