This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.
Host
Rabbit
Immunogen
hepatoma-derived growth factor (high-mobility group protein 1-like)
Isotype
IgG
Molecular Weight
38 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
HMG1L2
Uniprot
P51858
Gene Id
3068
Research Area
Cancer, Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)