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Home / Primary Antibodies / Polyclonal Antibodies

HDAC3 antibody

SKU : BHA10810276

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Mfr.No.	FNab10321
Background	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Clonality	polyclonal
Host	Rabbit
Immunogen	histone deacetylase 3
Immunogen Region	histone deacetylase 3
Isotype	IgG
Molecular Weight	49 kDa
Reactivity	Human
Recommended Dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Synonyms	HD3, RPD3, RPD3-2, HDAC3

Uniprot	O15379
Gene Id	8841
Research Area	Epigenetics, Cardiovascular, Metabolism

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10321.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810276	FNab10321	100ug	$240		Add to Cart

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