HCLS1 (hematopoietic cell-specific Lyn substrate 1) is a protein-coding gene. Diseases associated with HCLS1 include chronic lymphocytic leukemia. GO annotations related to this gene include protein kinase binding and protein complex binding. An important paralog of this gene is DBN1.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
Host
Rabbit
Immunogen
hematopoietic cell-specific Lyn substrate 1
Isotype
IgG
Molecular Weight
72 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
HS1
Uniprot
P14317
Gene Id
3059
Research Area
Immunology, Signal Transduction, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)