This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA.
Host
Rabbit
Immunogen
hydroxyacyl-Coenzyme A dehydrogenase
Isotype
IgG
Molecular Weight
33 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
HAD, HADHSC, SCHAD
Uniprot
Q16836
Gene Id
3033
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)