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Home / Primary Antibodies / Polyclonal Antibodies

GZMB antibody

SKU : BHA10803731

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Mfr.No.	FNab03737
Alternative Names	CGL1 ; CSPB ; CTLA1 ; GRB
Background	This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases(aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating apoptosis.
Categories	Primary Antibodies
Clonality	polyclonal
Description	This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Host	Rabbit
Immunogen	granzyme B
Isotype	IgG
Molecular Weight	33 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	CCPI, CGL 1, CGL1, CSP B, CSPB, CTLA1, CTSGL1, Endogenous granzyme B, Granzyme B, GZMB, HLP, SECT

Uniprot	P10144
Gene Id	3002
Research Area	Cancer, Immunology, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IF
Description	ELISA ; WB ; IHC ; IF
Tested Application	WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500

Manual	FNab03737.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803731	FNab03737	100ug	$280		Add to Cart

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