May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer(USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 (By similarity).
Host
Rabbit
Immunogen
GTF2I repeat domain containing 1
Isotype
IgG
Molecular Weight
145 kDa, 120 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12
Uniprot
Q9UHL9
Gene Id
9569
Research Area
Developmental biology, Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)