Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair(NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C- terminus is required for a successful escape of RNAP II form the promoter.
Host
Rabbit
Immunogen
general transcription factor IIH, polypeptide 2, 44kDa
Isotype
IgG
Molecular Weight
44kd
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
BTF2P44
Antigen
GTF2H2
Uniprot
Q13888
Gene Id
2966
Research Area
Metabolism, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)