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Home / Primary Antibodies / Polyclonal Antibodies

GSTA2 antibody

SKU : BHA10803681

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Mfr.No.	FNab03687
Alternative Names	GST2
Background	Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti- cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Host	Rabbit
Immunogen	glutathione S-transferase alpha 2
Isotype	IgG
Molecular Weight	25 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	Glutathione S transferase A2, GST class alpha member 2, GST gamma, GST HA subunit 2, GST2, GSTA2, GSTA2 2, GTA2, GTH2

Uniprot	P09210
Gene Id	2939
Research Area	Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC
Description	ELISA ; WB ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab03687.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803681	FNab03687	100ug	$240		Add to Cart

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