The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Clonality
monoclonal
Host
Mouse
Immunogen
glycogen synthase kinase 3 beta
Immunogen Region
glycogen synthase kinase 3 beta
Isotype
IgG1
Molecular Weight
47 kDa
Reactivity
Human, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Uniprot
P49841
Gene Id
2932
Clone No
5F4
Form
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10503.pdf" target="_blank">Data Sheet</ a>