Plays an important role in mitotic spindle pole organization via its interaction with NUMA1(PubMed:15632202, PubMed:21816348). Plays an important role in asymmetric cell divisions(PubMed:21816348). Has guanine nucleotide dissociation inhibitor(GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity(By similarity).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 (PubMed:15632202, PubMed:21816348). Plays an important role in asymmetric cell divisions (PubMed:21816348). Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity (By similarity).
Host
Rabbit
Immunogen
G-protein signaling modulator 2(AGS3-like, C. elegans)
Isotype
IgG
Molecular Weight
66-70 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
LGN
Uniprot
P81274
Gene Id
29899
Research Area
Cell Division and Proliferation, Signal Transduction
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)