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Home / Primary Antibodies / Polyclonal Antibodies

GPR177 antibody

SKU : BHA10803595

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Mfr.No.	FNab03601
Background	GPR177, also known as Wntless (WLS) or Evi, is an evolutionarily conserved transmembrane protein necessary for Wnt protein secretion. GPR177 localizes to compartments of the secretory pathway, including the ER, Golgi apparatus, endosomes, and plasma membrane. GPR177 is overexpressed in several cancer types including glioma and gastric cancer. Several isoforms of GPR177 exist due to the alternative splicing, with predicted MW around 62 and 51 kDa, respectively. The sequence can be processed by removing the signal peptide, which generates a mature form of 45-46 kDa. In addition, slow migragrating band above 62 kDa can also be detected because GPR177 is modified by N-linked glycosylation (PMID: 20549736).
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	G protein-coupled receptor 177
Isotype	IgG
Molecular Weight	46-62 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	C1orf139, EVI, G protein coupled receptor 177, GPR177, Protein wntless homolog, Sprinter, WLS, Wntless

Uniprot	Q5T9L3
Gene Id	79971
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:20-1:200

Manual	FNab03601.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803595	FNab03601	100ug	$260		Add to Cart

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