The C9orf72 "GGGGCC" repeat sequence codes five repeat peptide "GA repeat; GAGAGAGAGA", "GP repeat; GPGPGPGPG", "GR repeat; GRGRGRGRG", "AP repeat; APAPAPAPA" and "PR repeat; PRPRPRPRP". It was described previously that aggregated forms of poly-GA and poly-GP proteins do not enter the separation gel (PMID: 26374446). This antibody is used to detect the GP repeated sequence. The recombinant protein with 6*His tag or GST tag which contains the sequence GPGPGPGPG were used to detect this antibody.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
GP repeat
Isotype
IgG
Reactivity
Human
Regulatory
RUO
Synonyms
C9RAN, GGGCC, GP repeat, GPGPGPGP, poly GP, poly PG
Antigen
GP repeat
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)