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Home / Primary Antibodies / Polyclonal Antibodies

GOT1 antibody

SKU : BHA10809868

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Mfr.No.	FNab09876
Background	Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase(3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
Clonality	polyclonal
Host	Rabbit
Immunogen	glutamic-oxaloacetic transaminase 1, soluble(aspartate aminotransferase 1)
Immunogen Region	glutamic-oXaloacetic transaminase 1, soluble(aspartate aminotransferase 1)
Isotype	IgG
Molecular Weight	43-46 kDa
Reactivity	Human, Mouse, Rat
Recommended Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100
Synonyms	AATC, CAT, GIG18, GOT1, Transaminase A

Uniprot	P17174
Gene Id	2805
Research Area	Metabolism, Neuroscience

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab09876.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809868	FNab09876	100ug	$260		Add to Cart

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