Receptor for gonadotropin releasing hormone(GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone(LH) and follicle-stimulating hormone(FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.
Categories
Primary Antibodies
Cellular Localization
Membrane
Clonality
polyclonal
Description
Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle- stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol- calcium second messenger system. Isoform 2 may act as an inhibitor of GnRH-R signaling.
Host
Rabbit
Immunogen
gonadotropin-releasing hormone receptor
Isotype
IgG
Molecular Weight
38 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Subcellular Location
Cell membrane
Synonyms
GRHR
Uniprot
P30968
Gene Id
2798
Research Area
Developmental biology, Signal Transduction, Neuroscience
Weight
38kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)