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Home / Primary Antibodies / Polyclonal Antibodies

GLRB antibody

SKU : BHA10803483

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Mfr.No.	FNab03489
Background	Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine(PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1(PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability(PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents(PubMed:25445488).
Categories	Primary Antibodies
Clonality	polyclonal
Description	Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine (PubMed:8717357, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:25445488, PubMed:11929858, PubMed:23238346). Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA1 (PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488).
Host	Rabbit
Immunogen	glycine receptor, beta
Isotype	IgG
Molecular Weight	56 kDa
Reactivity	Human, Mouse
Regulatory	RUO

Uniprot	P48167
Gene Id	2743
Research Area	Developmental biology, Signal Transduction, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803483	FNab03489	100ug	$260		Add to Cart

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