SLC1A3, also known as EAAT-1 or GLAST, is a membrane-bound protein localized in glial cells and pre-synaptic glutamatergic nerve endings. It transports the excitatory neurotransmitters L-glutamate and D-aspartate, which is essential for terminating the postsynaptic acction of glutamate.Variety of bands can be observed in the western blotting assay: 50-55 kDa represents the unglycosylated GLAST1a or GLAST1b, 65-70 kDa correspond to the glycosylated proteins, larger proteins between 90-130 kDa may be the multimers of SLC1A3.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
Excitatory amino acid transporter 1
Isotype
IgG
Molecular Weight
50-55, 65-70 kDa, 90-100 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
EA6, EAAT1, GLAST, GLAST 1, GLAST1, SLC1A3
Uniprot
P43003
Research Area
Stem Cells, Signal Transduction, Metabolism, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)