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Home / Primary Antibodies / Polyclonal Antibodies

GDI1 antibody

SKU : BHA10803398

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Mfr.No.	FNab03404
Alternative Names	GDIL ; OPHN2 ; RABGDIA ; XAP4
Background	GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
Host	Rabbit
Immunogen	GDP dissociation inhibitor 1
Isotype	IgG
Molecular Weight	55 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	GDIL, OPHN2, RABGDIA, XAP4

Uniprot	P31150
Gene Id	2664
Research Area	Signal Transduction, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC, WB, IP
Description	ELISA ; IHC ; WB ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab03404.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10803398	FNab03404	100ug	$240		Add to Cart

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